摘要：光学相干断层成像技术(Optical coherence tomography，简称OCT），利用宽带光源的低相干性来实现实时、在体、无创、高分辨率的光学层析成像。最初的OCT为时域OCT，继而出现了扫频OCT，然后发展到谱域OCT。与前两者相比，谱域OCT具有成像速度快、成像质量好的优势，迅速成为生物医学成像领域研究的热点之一。61959

     本论文首先论述了OCT的起源与当前的发展现状,比较了时域OCT与频域OCT;然后深入研究了频域OCT的原理（包括光源的选用、深度信息的重建、光谱仪的设计）以及系统的组成、各部分的特点。并在此基础上,搭建了一套频域OCT实验平台,且进行了初步的验证性实验,对实验结果进行了分析并指出了影响该系统性能的因素。

毕业论文关键词： OCT；谱域OCT；光谱仪；干涉仪；视网膜成像

Research of optical coherence tomography experimental system

Abstract: Optical coherence tomography ( Acronym OCT), using broadband low-coherence light source to achieve real-time, in vivo, non-invasive, high-resolution optical tomographic imaging.The initial OCT is Time-Domain Optical Coherence Tomography ( Acronym TD-OCT) , was followed by Sweep source OCT  ( Acronym SS-OCT), and then developed into Spectral-domain OCT ( Acronym SD-OCT). Compared with the previous , it has high imaging speed, good image quality , and quickly became one of the focuses of biological research field of medical imaging.

   This paper first discusses the origin and current development of the OCT, relatively Time-Domain OCT and Frequency-Domain OCT; then further study of the principles of Frequency-Domain OCT (including selection of the light source, depth information reconstruction and spectrometer designing ) and the composition of system and characteristics of the various parts. And on this basis, to build a set of Frequency-Domain OCT experimental platform, and do preliminary validation experiments, the experimental results were analyzed and then point out the factors that affect the performance of the system.

 Keywords: OCT; SD-OCT; Spectrometer; Interferometer; Retinal Imaging

 摘要 i

Abstract i

目录 ii

1 绪论 1

1.1 课题背景及研究意义 1

1.2 OCT的研究现状和发展趋势 2

  1.2.1研究现状 2

  1.2.2发展趋势 3

1.3时域OCT与频域OCT的比较 4

1.4论文的主要研究内容 6

2 OCT系统原理 7

2.1 OCT的基本原理 7

2.2  OCT的光源及其与分辨率的计算 12

2.3  重建深度信息 13

  2.4  光谱仪的设计...14

3 实验系统搭建 17

3.1 实验器件 17

3.2  硬件系统 17

3.3 实验结果 19