摘    要

目的 了解空腹血糖受损人群的血脂特点，及其对糖尿病转归的影响，为预测及预防糖尿病发生发展提供新思路。方法 2014年在中国人民解放军第117医院体检中心选择上海某公安分局2255人作为调查对象，其中空腹血糖受损者235人，糖代谢正常者2020人，运用描述性分析，单因素分析和多项Logistic回归分析，分析空腹血糖受损人群的血脂特点及2年后对糖尿病转归的影响。结果 空腹血糖受损组的甘油三酯水平、总胆固醇水平、低密度脂蛋白胆固醇水平均高于糖代谢正常组，且差异具有统计学意义（P<0。05）。空腹血糖受损组的高密度脂蛋白水平低于糖代谢正常组，差异无统计学意义（P>0。05）。2年后在糖代谢正常组、空腹血糖受损组、糖尿病组中，甘油三酯水平逐渐升高，且差异具有统计学意义（P<0。05），总胆固醇水平、低密度脂蛋白胆固醇水平逐渐升高，差异无统计学意义（P>0。05），高密度脂蛋白胆固醇水平逐渐递减，且差异具有统计学意义（P<0。05）。以糖代谢正常组为对照组，高密度脂蛋白胆固醇与糖尿病的转归结果相关，且结果具有统计学意义（P<0。05）。结论 空腹血糖受损人群的甘油三酯水平、总胆固醇水平、低密度脂蛋白胆固醇水平均比普通人群高，高密度脂蛋白胆固醇可作为预测糖尿病发生的重要因素，并为糖尿病的预防提供重要思路。85172

AbstractObjective To understand the characteristics of blood lipid of people with impaired fasting glucose, and their effect on the reattribution of diabetes, to provide new ideas for predicting and preventing the development of diabetes。Methods In 2014,from the medical examination center of Chinese people's liberation army 117 hospital 2255 people randomly selected as the research object,including 235 impaired fasting glucose,2020 normal glucose metabolism，using descriptive analysis, single factor analysis and multiple Logistic regression analysis, analysis of the characteristics of the blood lipid impaired fasting glucose and effects on diabetes outcome after two years。Results The levels of triglyceride, total cholesterol and low-density lipoprotein cholesterol in the impaired fasting glucose group are higher than those in the normal glucose metabolism group, and the difference is statistically significant (P<0。05)。 The levels of high density lipoprotein (HDL) in the impaired fasting glucose group are lower than those in the normal glucose metabolism group (P>0。05)。 After two years, in the normal glucose group, impaired fasting glucose group, diabetes group, triglyceride levels increased gradually, and the difference is statistically significant (P<0。05), total cholesterol, low density lipoprotein cholesterol levels increased gradually, the difference is not statistically significant (P>0。05), high density lipoprotein cholesterol levels gradually decreased, and the difference is statistically significant (P<0。05)。 In the normal glucose metabolism group, the high density lipoprotein cholesterol (HDL-C) have an effect on the outcome of diabetes mellitus, and the results are statistically significant (P<0。05)。Conclusion People with impaired fasting blood glucose levels of triglycerides, total cholesterol, low density lipoprotein cholesterol levels were higher than in the general population, high density lipoprotein cholesterol can be used as important factors predict the development of diabetes mellitus, provides important insights into the prevention of diabetes。

毕业论文关键词：糖尿病前期;空腹血糖受损；糖尿病转归；血脂

Key words：Prediabetes; Impaired fasting glucose; Diabetes outcome; Blood lipid

目   录

1。 对象与方法 5

1。1调查对象