摘要本课题首先以水合肼、硝酸胍、乙酰丙酮为起始原料，分别经过胺化反应、成环反应和氧化脱氢反应合成重要前体3,6-双(3,5-二甲基吡唑)-s-四嗪(BT)，并对其合成工艺条件进行了优化，得到了较佳的反应条件。其次以3,6-双(3,5-二甲基吡唑)-s-四嗪为前体合成最终产物3,6-二肼基-s-四嗪(BHT)，并对其合成工艺条件进行了优化，得到了较佳的反应条件。最后，利用DSC对其热稳定性进行研究。64149

以BHT为前体进行重氮化反应合成叠氮杂环化合物3,6-二（叠氮基)-1,2,4,5 –四嗪(DiAT)。并通过13C核磁共振验证其叠氮-四唑的互变异构和四唑转型的特性。

毕业论文关键词  高氮含能化合物  3, 6-二肼基-1, 2, 4, 5-四嗪  DSC  热稳定性 

毕业设计说明书（论文）外文摘要

Title   Studies on the Synthesis and Stability of BHT                                          

Abstract In this paper, 3, 6-bis(3,5-dimethylpyrazol-1-yl)-s-tetrazine(BT) which is an  important precursor of  s-tetrazine type high-nitrogen compounds was synthesized with guanidine nitrate, hydrazine hydrate and acetylacetone as the raw materials. The 

synthesis process was optimized and the optimum conditions were obtained. 3,6-di(hydrazino)-1,2,4,5-tetrazine(BHT) was then synthesized from hydrazine hydrate and 3,6-bis(3,5-dimethylpyrazol-1-yl)-s-tetrazine(BT)  . The synthesis process was optimized and the optimum conditions were obtained. Finally, DSC was used to study the thermal stability of BHT.

3,6-diazido-1,2,4,5-tetrazine(DiAT) was synthesized from BHT by diazotization.The azido-tetrazolo tautomerization and tetrazolo transformation of 3,6-diazido -1,2, 4, 5 - tetrazine (DiAT) were investigated by the 13CNMR study.

Keywords   high-nitrogen compounds   3,6-di(hydrazino)-1,2,4,5-tetrazine  differential scanning calorimetry   thermal stability

1  绪论 1

1.1  HiNC研究背景 1

1.2  四嗪类HiNC研究进展 2

1.3  研究内容 5

2  实验部分 7

2.1  实验条件 7

2.1.1  实验药品与试剂 7

2.1.2  实验仪器 7

2.1.3  仪器分析 8

2.2  三胺基硝酸胍（TAGN）的合成 11

2.2.1  合成路线 11

2.2.2  反应历程 11

2.2.3  合成步骤 11

2.2.4  工艺优化 12

2.2.5  小结 13

2.3  3,6-双(3,5-二甲基吡唑)-1,2-二氢-s-四嗪(BDT)的合成 13

2.3.1  合成路线 13

2.3.2  反应历程 14

2.3.3  合成步骤 14

2.3.4  工艺优化 14

2.3.4  小结 16

2.3.5  表征 16

2.4  3,6-双(3,5-二甲基吡唑)-s-四嗪(BT)的合成 16

2.4.1  合成路线