Acetyl-ferridyl chloride is a derivative of ferulic acid that inherits the antioxidant properties of ferulic acid and it is used as an intermediate in the fields of medicine, pesticides, cosmetics and food additives [8,9], although so far, The study of acetyl-ferulyl chloride is still in its infancy, but it is undeniable that it has a very promising prospect, whether it is in food and medicine, or very popular antioxidant cosmetics, there is a very promising possibility.

But also because it is a kind of new products, so there are few reports on its synthesis method, the access route is common through acetylated ferulic acid and chlorided acetyl ferulic acid [10]. The design use vanillin in sodium acetate and acetic anhydride in the role of the formation of acetyl ferulic acid direct reaction, and then chlorinated ferulic acid to generate acetyl feruloyl chloride, the reaction cycle is short, easy to operate, yield can achieve 79% [11]. Through the process designed, to make a scale production.

“ Food additives are the soul of the food industry, there is no food additives without modern food industry [12]. ” So as a new type of food antioxidants intermediates, acetyl-ferulyl chloride’s industrial production has a very important significance.