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When the control to change only the remaining conditions constant catalyst species, and the catalytic effect of polyethylene glycol 600 were compared TEBAC. The experimental data showed that, when done with TEBAC catalyst, the higher the yield, the catalytic effect is better, therefore TEBAC selected as a catalyst for industrial production.
When the control to change only the remaining conditions constant holding time, respectively, in the reaction was refluxed for 1h and 2h after two hours. The experimental results showed that the purity of the product is called heat two hours advertisements, yield better, so use insulation 2h production.
And because the desired reaction product is insoluble in water extraction, the crystal particles and other impurities are dissolved in the product water-soluble substance, the separation of the desired product is purified by simple washing with water can be used directly. Finally, considering that the reaction is a heterogeneous reaction, the autoclave was stirred with a choice of the reactor apparatus, convection-enhanced, increasing the mass transfer and heat transfer. But the reaction will be used during recrystallization volatile ethanol, the ethanol will direct air pollution emissions, and therefore the exhaust gas after the reaction need to be processed.
In summary, from a technical point of view, for the synthesis and recycling nitroanisole established route is feasible. At the same time, also taking into account the cost aspect, the source and the processing is possible. According to the market survey, after the implementation of the production, the production will have income.
Computing technology and production programs
6 Material balance
The process comprising the base with the reaction, methanol recovery, crystallization, washing and drying process, each step involving mass balance. So we need to be calculated separately for each step.
Because an annual output has been given, so the yield of each step down according to the original feeding amount calculated in accordance with the yield has to be calculated.
With alkali process yield was 100% so do not consider the loss, destructive and out of the same material.
The reaction yield was 93.55% so it is necessary to consider the loss to be taken into account when calculating this. Also because there are side reactions during the reaction, the consumption of feed to the secondary reaction should also be considered.
Recycling process is calculated to be considered separately calculate the two-phase materials.
Washing process to take into account the amount of water to be added.
In the process involving impurities which have to take into account the calculation.
7 Energy balance
Heat balance is also a major part of our design task book. We calculate the heat of reaction heat balance equation through the investigation, the molar heat capacity at constant pressure and heat of combustion data so be estimated by "Chemical Process Design Manual" and the corresponding formula. To calculate the energy production process indicators to selected advanced production technology.
1 设计依据和工艺路线
1.1 产品的生产和应用
对硝基苯甲醚在化学品的生产过程中是一个非常重要原料的各种染料和药物的制备方法。在染料工业中可以被用作中间体，制备色酚AS—OL、大红色酚B、直接湖蓝6B、活性深蓝KD7G等；在有机工业中可以用来做作为生产氨基苯甲醚、联大茴香醚等的原材料；在医药方面可以作为合成愈创木酚等；在印染工业中可以制造洁净剂Ls等。
其合成路线主要有以下3种：对硝基苯酚与氯甲烷反应法、对硝基氯苯与甲醇钠反应法和苯甲醚硝化法。对硝基苯酚与氯甲烷反应法和苯甲醚硝化法合成路线长，分离过程非常复杂，而且原料紧缺，不适合用来工业生产。目前，我国多采用对硝基氯苯法。在大量甲醇存在下与固体氢氧化钠在加压釜中反应约10～13h合成NPM。但是这个工艺存在着甲醇消耗量大，长时间的反应过程，较低的收率，生成的副产物较多，会严重环境污染等问题。
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