高效的表面衍生近红外电致发光量子点的计时电位法制备及其超灵敏芯片基离子
关键词 计时电位法 离子选择性
毕业设计说明书（论文）外文摘要
Title Chronopotentiometric Synthesis of Quantum Dots With
Efficient,Surface-Derived,Near-Infrared
Electrochemiluminescence For Ultrasensitive
Microchip-Based Ion-Selective Sensing
Abstract
A novel QD with near-infrared (NIR) electrochemiluminescence (ECL) emission was prepared electrolytically by hydrodynamic chronopotentiometry, using Unithiol, a clinically-known metalantidote, as the capping agent for the fabrication of an ultrasensitive ion-selective microchip. The proposed synthetic route as well as the optical properties of QD was clarified with both morphologic and spectroscopic characterizations. In air-saturated pH 8.0 phosphate buffer with dissolved oxygen as the endogenous coreactant, an intensive NIR-ECL emission at 692 nm arose which was ascribed to the unique surface states of multidentate-chelated QDs. By tuning electrolytes, a low-potential ECL peaking at −0.79 V (vs. Ag/AgCl) could further be achieved. Based on the validated competition of heavy metallic cations to the stabilizer, the ECL emission could be significantly quenched and a home-made ECL ion-selective chip was manufactured. It was further found that capping with cation exchange membrane enabled an accelerated adsorption of metal ions and sensitized the ECL signal. Using cupric cation as a model analyte, the devised sensor showed a linear range from 10.0 pM to 1.0 mM with a detection limit down to 6.7 pM; and was successfully practised in the direct detection of Bordeaux mixture as inorganic pesticide residue on the grape skin with high accuracy and selectivity. The proposed strategy could also be extended to quantify Hg2+ and Pb2+ with stronger thiol-bonding capability than Cd2+. The developed microsensing system with replicable one-step synthesis should facilitate the portable and integrated QD-based NIR-ECL applications for food hygiene inspection and environmental monitoring.
Keywords Chronopotentiometric Synthesis Ion-Selective
目 次
1 引言 1
2 实验部分 3
2.1 实验材料与仪器 3
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